definition for: #XplorerHT

At HEL we have used stringent design criteria to develop Xplorer HT, an automated parallel small scale bioreactor platform that can be used for microbial expression systems. Central to the design for this application are the following factors: Fully automated, independent reactor system. The ability to independently control and monitor every variable to changes between reactors and the possibility to alter conditions, in real time, is key to reducing development time. Small scale reactors that closely mimic pilot scale reactors. Work done with University College London demonstrates that small highly instrumented HEL bioreactors are capable of providing results comparable to those seen in large scale in batch and fed batch modes. Compact footprint for bench use and integration. The XplorerHT unit is the most compact unit available, reducing the impact on the laboratory bench space. Furthermore, deck based liquid handling robots are routinely used in high throughput screening campaigns and their versatility and sample collection abilities are ideal for strain selection and development processes. The HEL XplorerHT unit can be integrated with any robot deck thereby combining proven screening technologies into one powerful development platform. Modular system with an extensive portfolio of process development tools. By combining blocks of 8 mini- reactors a high throughput parallel platform can be quickly established . The reactors themselves can be populated with a range of tools. Further to the traditional temperature, DO and pH probes we also offer optical density, FTIR and bio-calorimetry probes. Options are also available for multi-way feed pumps for substrate addition and pH control as well as DO feedback control and gas blending to maximise cell densities.